SCPortalen


Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma.


Intratumoral heterogeneity hampers the success of marker-based anticancer treatment because the targeted therapy may eliminate a specific subpopulation of tumor cells while leaving others unharmed. Accordingly, a rational strategy minimizing survival of the drug-resistant subpopulation is essential to achieve long-term therapeutic efficacy. Using single-cell RNA sequencing (RNA-seq), we examine the intratumoral heterogeneity of a pair of primary renal cell carcinoma and its lung metastasis. Activation of drug target pathways demonstrates considerable variability between the primary and metastatic sites, as well as among individual cancer cells within each site. Based on the prediction of multiple drug target pathway activation, we derive a combinatorial regimen co-targeting two mutually exclusive pathways for the metastatic cancer cells. This combinatorial strategy shows significant increase in the treatment efficacy over monotherapy in the experimental validation using patient-derived xenograft platforms in vitro and in vivo. Our findings demonstrate the investigational application of single-cell RNA-seq in the design of an anticancer regimen. The approach may overcome intratumoral heterogeneity which hampers the success of precision medicine.

GSE73121 Samples



Cell Metadata and BAM Files

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BAM Files Run Accession Number Sample Accession Number Organism Organ/Tissue Dev. Stage Cell Type Sequencer Protocol Assay Type Library Layout Ontology Term Cell Cycle Phase
SRR2431343 SAMN04093546 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431344 SAMN04093547 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431345 SAMN04093548 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431346 SAMN04093549 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431347 SAMN04093550 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431348 SAMN04093551 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431349 SAMN04093552 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431350 SAMN04093553 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431351 SAMN04093554 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431352 SAMN04093555 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431353 SAMN04093556 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431354 SAMN04093557 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431355 SAMN04093558 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431356 SAMN04093559 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431357 SAMN04093560 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431358 SAMN04093561 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431359 SAMN04093562 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431360 SAMN04093563 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431361 SAMN04093564 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431362 SAMN04093565 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431363 SAMN04093566 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431364 SAMN04093567 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431365 SAMN04093568 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431366 SAMN04093569 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431367 SAMN04093570 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431368 SAMN04093574 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431369 SAMN04093575 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431370 SAMN04093637 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431371 SAMN04093638 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431372 SAMN04093639 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431373 SAMN04093571 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431374 SAMN04093572 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431375 SAMN04093573 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431376 SAMN04093640 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431377 SAMN04093641 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2.M
SRR2431378 SAMN04093642 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431379 SAMN04093643 Homo sapiens Kidney Adult Metastatic renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431380 SAMN04093644 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431381 SAMN04093645 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431382 SAMN04093646 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431383 SAMN04093647 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431384 SAMN04093648 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431385 SAMN04093649 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431386 SAMN04093650 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431387 SAMN04093651 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431388 SAMN04093652 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431389 SAMN04093653 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431390 SAMN04093654 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431391 SAMN04093655 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431392 SAMN04093656 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431393 SAMN04093657 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] M.G1
SRR2431394 SAMN04093658 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431395 SAMN04093659 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431396 SAMN04093660 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431397 SAMN04093661 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431398 SAMN04093662 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431399 SAMN04093663 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431400 SAMN04093664 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431401 SAMN04093665 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431402 SAMN04093666 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2.M
SRR2431403 SAMN04093607 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431404 SAMN04093608 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431405 SAMN04093609 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431406 SAMN04093610 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431407 SAMN04093611 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431408 SAMN04093612 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431409 SAMN04093613 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431410 SAMN04093614 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431411 SAMN04093615 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2.M
SRR2431412 SAMN04093616 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431413 SAMN04093617 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431414 SAMN04093618 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431415 SAMN04093619 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431416 SAMN04093620 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431417 SAMN04093621 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431418 SAMN04093622 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431419 SAMN04093623 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431420 SAMN04093624 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431421 SAMN04093625 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2.M
SRR2431422 SAMN04093626 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431423 SAMN04093627 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G1.S
SRR2431424 SAMN04093628 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431425 SAMN04093630 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431426 SAMN04093631 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] S
SRR2431427 SAMN04093632 Homo sapiens Kidney Adult Primary renal cell carcinoma Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0000037 [renal cell carcinoma cell] G2
SRR2431428 SAMN04093633 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431429 SAMN04093634 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431430 SAMN04093635 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431431 SAMN04093636 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431432 SAMN04093577 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431433 SAMN04093629 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431434 SAMN04093578 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431435 SAMN04093579 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431436 SAMN04093580 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431437 SAMN04093581 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431438 SAMN04093582 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431439 SAMN04093583 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431440 SAMN04093584 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431441 SAMN04093585 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431442 SAMN04093586 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431443 SAMN04093587 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431444 SAMN04093588 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431445 SAMN04093589 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431446 SAMN04093590 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431447 SAMN04093591 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431448 SAMN04093592 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431449 SAMN04093593 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431450 SAMN04093594 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431451 SAMN04093595 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G1.S
SRR2431452 SAMN04093596 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431453 SAMN04093597 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431454 SAMN04093598 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431455 SAMN04093599 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431456 SAMN04093600 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431457 SAMN04093602 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431458 SAMN04093603 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431459 SAMN04093604 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] G2
SRR2431460 SAMN04093605 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431461 SAMN04093606 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] M.G1
SRR2431462 SAMN04093576 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S
SRR2431463 SAMN04093601 Homo sapiens Kidney Adult Metastatic renal cell carcinom Illumina HiSeq 2500 SMARTer RNA-Seq Paired-End BTO:0005594[metastatic renal cell carcinoma cell] S

FASTQC Report



FASTQC File ID Cell Accession Number FASTQC Report Link No. Sequence Tags
SRR2431343_1 SRR2431343 Preview 3957722
SRR2431343_2 SRR2431343 Preview 3957722
SRR2431344_1 SRR2431344 Preview 3936241
SRR2431344_2 SRR2431344 Preview 3936241
SRR2431345_1 SRR2431345 Preview 2984402
SRR2431345_2 SRR2431345 Preview 2984402
SRR2431346_1 SRR2431346 Preview 3786746
SRR2431346_2 SRR2431346 Preview 3786746
SRR2431347_1 SRR2431347 Preview 3834968
SRR2431347_2 SRR2431347 Preview 3834968
SRR2431348_1 SRR2431348 Preview 4154963
SRR2431348_2 SRR2431348 Preview 4154963
SRR2431349_1 SRR2431349 Preview 2949363
SRR2431349_2 SRR2431349 Preview 2949363
SRR2431350_1 SRR2431350 Preview 2847400
SRR2431350_2 SRR2431350 Preview 2847400
SRR2431351_1 SRR2431351 Preview 3186145
SRR2431351_2 SRR2431351 Preview 3186145
SRR2431352_1 SRR2431352 Preview 2310593
SRR2431352_2 SRR2431352 Preview 2310593
SRR2431353_1 SRR2431353 Preview 5061971
SRR2431353_2 SRR2431353 Preview 5061971
SRR2431354_1 SRR2431354 Preview 3523905
SRR2431354_2 SRR2431354 Preview 3523905
SRR2431355_1 SRR2431355 Preview 3534835
SRR2431355_2 SRR2431355 Preview 3534835
SRR2431356_1 SRR2431356 Preview 2975639
SRR2431356_2 SRR2431356 Preview 2975639
SRR2431357_1 SRR2431357 Preview 1847762
SRR2431357_2 SRR2431357 Preview 1847762
SRR2431358_1 SRR2431358 Preview 3703491
SRR2431358_2 SRR2431358 Preview 3703491
SRR2431359_1 SRR2431359 Preview 3225750
SRR2431359_2 SRR2431359 Preview 3225750
SRR2431360_1 SRR2431360 Preview 3299572
SRR2431360_2 SRR2431360 Preview 3299572
SRR2431361_1 SRR2431361 Preview 7697391
SRR2431361_2 SRR2431361 Preview 7697391
SRR2431362_1 SRR2431362 Preview 3452287
SRR2431362_2 SRR2431362 Preview 3452287
SRR2431363_1 SRR2431363 Preview 3062293
SRR2431363_2 SRR2431363 Preview 3062293
SRR2431364_1 SRR2431364 Preview 6021825
SRR2431364_2 SRR2431364 Preview 6021825
SRR2431365_1 SRR2431365 Preview 5010061
SRR2431365_2 SRR2431365 Preview 5010061
SRR2431366_1 SRR2431366 Preview 6228201
SRR2431366_2 SRR2431366 Preview 6228201
SRR2431367_1 SRR2431367 Preview 4619755
SRR2431367_2 SRR2431367 Preview 4619755
SRR2431368_1 SRR2431368 Preview 3204563
SRR2431368_2 SRR2431368 Preview 3204563
SRR2431369_1 SRR2431369 Preview 6097386
SRR2431369_2 SRR2431369 Preview 6097386
SRR2431370_1 SRR2431370 Preview 4558867
SRR2431370_2 SRR2431370 Preview 4558867
SRR2431371_1 SRR2431371 Preview 4585865
SRR2431371_2 SRR2431371 Preview 4585865
SRR2431372_1 SRR2431372 Preview 4654982
SRR2431372_2 SRR2431372 Preview 4654982
SRR2431373_1 SRR2431373 Preview 5824419
SRR2431373_2 SRR2431373 Preview 5824419
SRR2431374_1 SRR2431374 Preview 3290898
SRR2431374_2 SRR2431374 Preview 3290898
SRR2431375_1 SRR2431375 Preview 3303143
SRR2431375_2 SRR2431375 Preview 3303143
SRR2431376_1 SRR2431376 Preview 3588590
SRR2431376_2 SRR2431376 Preview 3588590
SRR2431377_1 SRR2431377 Preview 2297107
SRR2431377_2 SRR2431377 Preview 2297107
SRR2431378_1 SRR2431378 Preview 4496194
SRR2431378_2 SRR2431378 Preview 4496194
SRR2431379_1 SRR2431379 Preview 2349845
SRR2431379_2 SRR2431379 Preview 2349845
SRR2431380_1 SRR2431380 Preview 3922748
SRR2431380_2 SRR2431380 Preview 3922748
SRR2431381_1 SRR2431381 Preview 3325870
SRR2431381_2 SRR2431381 Preview 3325870
SRR2431382_1 SRR2431382 Preview 3971678
SRR2431382_2 SRR2431382 Preview 3971678
SRR2431383_1 SRR2431383 Preview 3978527
SRR2431383_2 SRR2431383 Preview 3978527
SRR2431384_1 SRR2431384 Preview 2617901
SRR2431384_2 SRR2431384 Preview 2617901
SRR2431385_1 SRR2431385 Preview 3850968
SRR2431385_2 SRR2431385 Preview 3850968
SRR2431386_1 SRR2431386 Preview 4364531
SRR2431386_2 SRR2431386 Preview 4364531
SRR2431387_1 SRR2431387 Preview 4972026
SRR2431387_2 SRR2431387 Preview 4972026
SRR2431388_1 SRR2431388 Preview 3880705
SRR2431388_2 SRR2431388 Preview 3880705
SRR2431389_1 SRR2431389 Preview 4521451
SRR2431389_2 SRR2431389 Preview 4521451
SRR2431390_1 SRR2431390 Preview 3296883
SRR2431390_2 SRR2431390 Preview 3296883
SRR2431391_1 SRR2431391 Preview 4619639
SRR2431391_2 SRR2431391 Preview 4619639
SRR2431392_1 SRR2431392 Preview 3742836
SRR2431392_2 SRR2431392 Preview 3742836
SRR2431393_1 SRR2431393 Preview 3752017
SRR2431393_2 SRR2431393 Preview 3752017
SRR2431394_1 SRR2431394 Preview 4208269
SRR2431394_2 SRR2431394 Preview 4208269
SRR2431395_1 SRR2431395 Preview 3869846
SRR2431395_2 SRR2431395 Preview 3869846
SRR2431396_1 SRR2431396 Preview 2504966
SRR2431396_2 SRR2431396 Preview 2504966
SRR2431397_1 SRR2431397 Preview 3918778
SRR2431397_2 SRR2431397 Preview 3918778
SRR2431398_1 SRR2431398 Preview 3050834
SRR2431398_2 SRR2431398 Preview 3050834
SRR2431399_1 SRR2431399 Preview 2610400
SRR2431399_2 SRR2431399 Preview 2610400
SRR2431400_1 SRR2431400 Preview 2679199
SRR2431400_2 SRR2431400 Preview 2679199
SRR2431401_1 SRR2431401 Preview 4141346
SRR2431401_2 SRR2431401 Preview 4141346
SRR2431402_1 SRR2431402 Preview 4743158
SRR2431402_2 SRR2431402 Preview 4743158
SRR2431403_1 SRR2431403 Preview 3362018
SRR2431403_2 SRR2431403 Preview 3362018
SRR2431404_1 SRR2431404 Preview 3183772
SRR2431404_2 SRR2431404 Preview 3183772
SRR2431405_1 SRR2431405 Preview 3893213
SRR2431405_2 SRR2431405 Preview 3893213
SRR2431406_1 SRR2431406 Preview 4374582
SRR2431406_2 SRR2431406 Preview 4374582
SRR2431407_1 SRR2431407 Preview 3507256
SRR2431407_2 SRR2431407 Preview 3507256
SRR2431408_1 SRR2431408 Preview 3268090
SRR2431408_2 SRR2431408 Preview 3268090
SRR2431409_1 SRR2431409 Preview 4649506
SRR2431409_2 SRR2431409 Preview 4649506
SRR2431410_1 SRR2431410 Preview 3193036
SRR2431410_2 SRR2431410 Preview 3193036
SRR2431411_1 SRR2431411 Preview 7603
SRR2431411_2 SRR2431411 Preview 7603
SRR2431412_1 SRR2431412 Preview 3542954
SRR2431412_2 SRR2431412 Preview 3542954
SRR2431413_1 SRR2431413 Preview 2541583
SRR2431413_2 SRR2431413 Preview 2541583
SRR2431414_1 SRR2431414 Preview 3853193
SRR2431414_2 SRR2431414 Preview 3853193
SRR2431415_1 SRR2431415 Preview 4033895
SRR2431415_2 SRR2431415 Preview 4033895
SRR2431416_1 SRR2431416 Preview 3773900
SRR2431416_2 SRR2431416 Preview 3773900
SRR2431417_1 SRR2431417 Preview 4470602
SRR2431417_2 SRR2431417 Preview 4470602
SRR2431418_1 SRR2431418 Preview 4460269
SRR2431418_2 SRR2431418 Preview 4460269
SRR2431419_1 SRR2431419 Preview 3231120
SRR2431419_2 SRR2431419 Preview 3231120
SRR2431420_1 SRR2431420 Preview 3171465
SRR2431420_2 SRR2431420 Preview 3171465
SRR2431421_1 SRR2431421 Preview 3478811
SRR2431421_2 SRR2431421 Preview 3478811
SRR2431422_1 SRR2431422 Preview 4013650
SRR2431422_2 SRR2431422 Preview 4013650
SRR2431423_1 SRR2431423 Preview 3100541
SRR2431423_2 SRR2431423 Preview 3100541
SRR2431424_1 SRR2431424 Preview 3563750
SRR2431424_2 SRR2431424 Preview 3563750
SRR2431425_1 SRR2431425 Preview 3376461
SRR2431425_2 SRR2431425 Preview 3376461
SRR2431426_1 SRR2431426 Preview 4347118
SRR2431426_2 SRR2431426 Preview 4347118
SRR2431427_1 SRR2431427 Preview 3527338
SRR2431427_2 SRR2431427 Preview 3527338
SRR2431428_1 SRR2431428 Preview 7103232
SRR2431428_2 SRR2431428 Preview 7103232
SRR2431429_1 SRR2431429 Preview 4441898
SRR2431429_2 SRR2431429 Preview 4441898
SRR2431430_1 SRR2431430 Preview 8524753
SRR2431430_2 SRR2431430 Preview 8524753
SRR2431431_1 SRR2431431 Preview 36234
SRR2431431_2 SRR2431431 Preview 36234
SRR2431432_1 SRR2431432 Preview 2321354
SRR2431432_2 SRR2431432 Preview 2321354
SRR2431433_1 SRR2431433 Preview 4859399
SRR2431433_2 SRR2431433 Preview 4859399
SRR2431434_1 SRR2431434 Preview 5043176
SRR2431434_2 SRR2431434 Preview 5043176
SRR2431435_1 SRR2431435 Preview 5910354
SRR2431435_2 SRR2431435 Preview 5910354
SRR2431436_1 SRR2431436 Preview 4323732
SRR2431436_2 SRR2431436 Preview 4323732
SRR2431437_1 SRR2431437 Preview 3886813
SRR2431437_2 SRR2431437 Preview 3886813
SRR2431438_1 SRR2431438 Preview 4134399
SRR2431438_2 SRR2431438 Preview 4134399
SRR2431439_1 SRR2431439 Preview 10640979
SRR2431439_2 SRR2431439 Preview 10640979
SRR2431440_1 SRR2431440 Preview 12859956
SRR2431440_2 SRR2431440 Preview 12859956
SRR2431441_1 SRR2431441 Preview 3522182
SRR2431441_2 SRR2431441 Preview 3522182
SRR2431442_1 SRR2431442 Preview 1529124
SRR2431442_2 SRR2431442 Preview 1529124
SRR2431443_1 SRR2431443 Preview 7283159
SRR2431443_2 SRR2431443 Preview 7283159
SRR2431444_1 SRR2431444 Preview 7141576
SRR2431444_2 SRR2431444 Preview 7141576
SRR2431445_1 SRR2431445 Preview 4329276
SRR2431445_2 SRR2431445 Preview 4329276
SRR2431446_1 SRR2431446 Preview 5310685
SRR2431446_2 SRR2431446 Preview 5310685
SRR2431447_1 SRR2431447 Preview 6224420
SRR2431447_2 SRR2431447 Preview 6224420
SRR2431448_1 SRR2431448 Preview 2145508
SRR2431448_2 SRR2431448 Preview 2145508
SRR2431449_1 SRR2431449 Preview 3369652
SRR2431449_2 SRR2431449 Preview 3369652
SRR2431450_1 SRR2431450 Preview 4457863
SRR2431450_2 SRR2431450 Preview 4457863
SRR2431451_1 SRR2431451 Preview 5924803
SRR2431451_2 SRR2431451 Preview 5924803
SRR2431452_1 SRR2431452 Preview 6070143
SRR2431452_2 SRR2431452 Preview 6070143
SRR2431453_1 SRR2431453 Preview 4187303
SRR2431453_2 SRR2431453 Preview 4187303
SRR2431454_1 SRR2431454 Preview 4777075
SRR2431454_2 SRR2431454 Preview 4777075
SRR2431455_1 SRR2431455 Preview 1999699
SRR2431455_2 SRR2431455 Preview 1999699
SRR2431456_1 SRR2431456 Preview 9170196
SRR2431456_2 SRR2431456 Preview 9170196
SRR2431457_1 SRR2431457 Preview 4573485
SRR2431457_2 SRR2431457 Preview 4573485
SRR2431458_1 SRR2431458 Preview 5449301
SRR2431458_2 SRR2431458 Preview 5449301
SRR2431459_1 SRR2431459 Preview 4074507
SRR2431459_2 SRR2431459 Preview 4074507
SRR2431460_1 SRR2431460 Preview 4528867
SRR2431460_2 SRR2431460 Preview 4528867
SRR2431461_1 SRR2431461 Preview 6678745
SRR2431461_2 SRR2431461 Preview 6678745
SRR2431462_1 SRR2431462 Preview 2035806
SRR2431462_2 SRR2431462 Preview 2035806
SRR2431463_1 SRR2431463 Preview 3797315
SRR2431463_2 SRR2431463 Preview 3797315


Organism : Homo sapiens

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File Size : 305M

Human Cell Data

Image Currently Unavailable
tSNE image.
Image Currently Unavailable
PCA image.
Image Currently Unavailable
Gene Body Coverage image.

Data Resources


Organism Run Metadata Link Data Repository Link Pubmed Record Link Author Provided Files DAVID Annotation Chart Link DAVID Annotation Table Link Gene Body Coverage Matrix Link PCA Matrix Link Krona Plot Img Link Unmapped Reads Link Expression Correlation
Homo sapiens